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Volume 5 No. 4
05 December 2019
Special Issue on Surgical Treatments for Cerebral Palsy

Ruolei Gu, Jie Liu, Fang Cui

2019, 5(4): 221-238.   doi:10.26599/BSA.2019.9050020
Abstract ( 172 HTML ( 21   PDF(1081KB) ( 96 )   Save

This paper focuses on the social function of painful experience as revealed by recent studies on social decision-making. Observing others suffering from physical pain evokes empathic reactions that can lead to prosocial behavior (e.g., helping others at a cost to oneself), which might be regarded as the social value of pain derived from evolution. Feelings of guilt may also be elicited when one takes responsibility for another’s pain. These social emotions play a significant role in various c...

Karen M. von Deneen, Ling Zhao, Jixin Liu

2019, 5(4): 239-255.   doi:10.26599/BSA.2019.9050021
Abstract ( 70 HTML ( 4   PDF(803KB) ( 35 )   Save

Migraine is a difficult disorder to identify with regard to its pathophysiological mechanisms, and its treatment has been primarily difficult owing to interindividual differences. Substantial rates of nonresponsiveness to medications are common, making migraine treatment complicated. In this review, we systematically analyzed recent studies concerning neuroimaging findings regarding the neurophysiology of migraine. We linked the current imaging research with anecdotal evidence from interindiv...

Xiong Li, Yinya Zhang, Binyang Xiang, Jing Meng

2019, 5(4): 256-264.   doi:10.26599/BSA.2019.9050022
Abstract ( 146 HTML ( 0   PDF(932KB) ( 67 )   Save

Empathy for pain is a hotspot in the field of empathy research because of its specific cognitive and neural mechanism. Currently, studies of empathy for pain can be classified into two categories based on the body regions receiving the painful stimulus, i.e., empathy for face pain and empathy for body pain, which conveys painful information based on individuals’ faces or body parts, respectively. Although the existing evidence revealed differences between these two kinds of pain empathy regar...

Ming Zhang, Yuqi Zhang, Yazhuo Kong

2019, 5(4): 265-273.   doi:10.26599/BSA.2019.9050023
Abstract ( 149 HTML ( 3   PDF(933KB) ( 94 )   Save

People often experience two types of pain: social pain and physical pain. The former is related to psychological distance from other people or social groups, whereas the latter is associated with actual or potential tissue damage. Social pain caused by interpersonal interactions causes negative feelings in individuals and has negative consequences to the same degree as physical pain. Various studies have shown an interaction between social pain and physical pain, not only in behavioral perfor...

Qian Su, Yingchao Song, Rui Zhao, Meng Liang

2019, 5(4): 274-287.   doi:10.26599/BSA.2019.9050024
Abstract ( 74 HTML ( 4   PDF(856KB) ( 85 )   Save

Developing an objective biomarker for pain assessment is crucial for understanding neural coding mechanisms of pain in the human brain as well as for effective treatment of pain disorders. Neuroimaging techniques have been proven to be powerful tools in the ongoing quest for a pain signature in the human brain. Although there is still a long way to go before achieving a truly successful pain signature based on neuroimaging techniques, important progresses have been made through great efforts ...

Tahmineh Mokhtari, Yiheng Tu, Li Hu

2019, 5(4): 288-298.   doi:10.26599/BSA.2019.9050025
Abstract ( 60 HTML ( 4   PDF(895KB) ( 42 )   Save

Increases in depressive behaviors have been reported in patients experiencing chronic pain. In these patients, the symptoms of pain and depression commonly coexist, impairing their lives and challenging effective treatment. The hippocampus may play a role in both chronic pain and depression. A reduction in the volume of the hippocampus is related to reduced neurogenesis and neuroplasticity in cases of chronic pain and depression. Moreover, an increase of proinflammatory factors and a reductio...