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Volume 4 No. 2
05 December 2018

Tonghui Su, Yi Lu, Yang Geng, Wei Lu, Yelin Chen

2018, 4(2): 73-98.   doi:10.26599/BSA.2018.2018.9050009
Abstract ( 10 HTML ( 0   PDF(785KB) ( 11 )   Save

N-methyl-D-aspartate receptors (NMDARs) are a family of ionotropic glutamate receptors mainly known to mediate excitatory synaptic transmission and plasticity. Interestingly, low-dose NMDAR antagonists lead to increased, instead of decreased, functional connectivity; and they could cause schizophrenia- and/or antidepressant-like behavior in both humans and rodents. In addition, human genetic evidences indicate that NMDAR loss of function mutations underlie certain forms of epilepsy, a disease...

Yang Yang, Ju Lu, Yi Zuo

2018, 4(2): 99-117.   doi:10.26599/BSA.2018.2018.9050012
Abstract ( 9 HTML ( 2   PDF(620KB) ( 3 )   Save

Synaptic plasticity is widely believed to be the cellular basis of learning and memory. It is influenced by various factors including development, sensory experiences, and brain disorders. Long-term synaptic plasticity is accompanied by protein synthesis and trafficking, leading to structural changes of the synapse. In this review, we focus on the synaptic structural plasticity, which has mainly been studied with in vivo two-photon laser scanning microscopy. We also discuss how a speci...

Hongyi Zhao, Dandan Li, Xiuzhen Li

2018, 4(2): 118-130.   doi:10.26599/BSA.2018.9050005
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Dreaming is a ubiquitous phenomenon in human beings and has been discussed, researched, and hypothesized since a long time. The substrate, physiological mechanism, and function of dreaming have been explained by many scientists from the neurological, psychiatric, psychological, and philosophical perspective. With the development of scientific technology, many theories of dreaming have been established. In the present review, we first summarize the different theories of dreaming; furthermore, ...

Tuoyu Chen, Lin Chen, Xin Pan, Chaoqiang Xue, Qinglin Zhang, Yuqi Zhang

2018, 4(2): 131-140.   doi:10.26599/BSA.2018.2018.9050011
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The aim of the current study was to investigate the operation skills and complications associated with skull defect repair using biomimetic bone (nano-hap/collagen composites). Clinical data from 45 patients with skull defects who underwent cranioplasty with biomimetic bone from January 2014 to January 2017 were retrospectively analyzed. All patients participated in follow-up visits from 8 months to 3 years postoperatively. Cranioplasties were successful in all 45 patients, but 17 patients (2...

Ismatullah Soufiany, Khalil Ahmad Hijrat, Spina Soufiany, Lukui Chen

2018, 4(2): 141-155.   doi:10.26599/BSA.2018.9050002
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A ventriculoperitoneal shunt (VPS) is a medical device used to deflect cerebrospinal fluid from cerebral ventricles to the peritoneal cavity. Since 1908, ventriculoperitoneal shunts have been considered the best option in hydrocephalus management. Manifestation related to VPS may arise anywhere whilst tunneling the VPS from the ventricle to the peritoneal cavity, but complications associated with the distal catheter are especially common and a leading cause of revision surgeries. Among the ma...

Wenchang Zhang, Chuanqi Tan, Fuchun Sun, Hang Wu, Bo Zhang

2018, 4(2): 156-167.   doi:10.26599/BSA.2018.9050010
Abstract ( 12 HTML ( 1   PDF(552KB) ( 10 )   Save

A brain-computer interface (BCI) system can recognize the mental activities pattern by computer algorithms to control the external devices. Electroencephalogram (EEG) is one of the most common used approach for BCI due to the convenience and non-invasive implement. Therefore, more and more BCIs have been designed for the disabled people that suffer from stroke or spinal cord injury to help them for rehabilitation and life. We introduce the common BCI paradigms, the signal processing, and feat...